Gabriella Brandimarte Queiroz, João Lopes Neto, Augusto Foggiato, Douglas Fernandes Silva


Cell death is an essential biological process for physiological growth and development. Therefore, this process has different types of cell death and the main three are: apoptosis, autophagy and necrosis. In addition, cell death is related to manifestations of various diseases and treatment of systemic diseases in the areas of general health, such as cancer and periodontitis, in addition to viruses. In this study, the importance of cell death for the organism and its relationship with various human diseases, such as the new coronavirus 2 respiratory syndrome (SARS-CoV-2), both in clinical manifestations and in possible treatments, such as tumor necrosis agents (anti -TNF), to improve the response rates of patients with inflammatory diseases or the importance of lymphocytic apoptosis, promoted by SARS-CoV-2 by increasing the expression of Fas. Through this study it was possible to identify the importance of cell death for the organism and how it can interfere in human diseases; thus, enable the biotechnological application in the development of specific drugs and therapies.


Apoptosis; necrosis; autophagy; Health;


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